Could Sleeping Beauty have been a haemophiliac?

Sarah Hume


In the fairy tale Sleeping Beauty pricks her finger on a spindle and due to a curse placed on her as a baby, falls to sleep for a hundred years. Here we explore the ramifications of a scenario where instead of a curse, Sleeping Beauty has haemophilia and cuts her finger at age seventeen. We first establish that to have reached her age without modern medicine, it is most likely the princess has a mild form of the disease. A model is then constructed resulting in the conclusion that if Sleeping Beauty was a haemophiliac, a relatively minor cut to her hand left untreated would be sufficient for her to ‘fall into a slumber’ as in the story or, put simply, faint.


Fairy Tale; Biology: Haemotology; Haemophilia; Sleeping Beauty

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Grimm Brothers (1917) ‘Sleeping Beauty’, Fairy Tales and Other Traditional Stories, Lit2Go Edn. Available at: (Accessed: 4 March 2022).

NHS (2020) Haemophilia. Available at: (Accessed: 3 March 2022).

NHS Health Education England (2020) Haemophilia A and B. Available at: (Accessed: 3 March 2022).

Graw, J., Brackmann, H.H., Oldenburg, J., Schneppenhein, R., Spannagl, M. and Schwaab, R. (2005) Haemophilia A: from mutation analysis to new therapies, Nature Reviews Genetics, 6, pp. 488-501. DOI: 10.1038/nrg1617

Savage, N. (2013) Clotting factors: Stretching time, Nature, 515, pp. S162-S164. DOI: 10.1038/515S162a

Imperial College Healthcare NHS Trust (2018) Mild or moderate haemophilia – how will it affect my life? Information for patients. Available at: (Accessed: 6 March 2022).

Guitierrez, G., Reines, H.D. and Wulf-Guitierrez. (2004) Clinical review: Hemorrhagic shock, Critical Care, 8(5), pp. 373-381. DOI: 10.1186/cc2851

Sharma, R. and Sharma, S. (2021) Physiology, Blood Volume, Florida: StatPearls Publishing.

Peters, A.M. (2018) The precise physiological definition of tissue perfusion and clearance measured from imaging, European Journal of Nuclear Medicine and Molecular Imaging, 45, pp. 1139-1141. DOI: 10.1007/s00259-018-3982-7


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